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Clinical Trials

What is a Clinical Trial?

A clinical trial is a research study designed to answer one or more questions about how a certain drug, treatment or medical device affects a disease. Some clinical trials compare existing treatments to determine which is better. There are potential benefits to participating in a clinical trial, as well as potential risks.

By participating in a clinical trial, you can help our doctors take the next steps in discovering new ways to treat and prevent cancer. Please take a moment to review the Protocols open for enrollment below.

Clinical trials are being offered now. For more information please contact our research department at 606-435-7202.


Protocol #CP-MGAH-22-04 (SOPHIA)
A Phase 3, Randomized study of Margetuximab plus chemotherapy vs Trastuzumab plus chemotherapy in the treatment of patients with HER2+ metastatic breast cancer who have received two prior Anti-HER2 therapies and require systemic treatment.

Protocol #BGB-A317-NSCL-001
A PHASE 3, RANDOMIZED, BLINDED, PLACEBO CONTROLLED STUDY OF TISLELIZUMAB (BGB-A317) PLUS CHEMORADIOTHERAPY FOLLOWED BY TISLELIZUMAB MONOTHERAPY IN NEWLY DIAGNOSED, STAGE III SUBJECTS WITH LOCALLY ADVANCED, UNRESECTABLE NON-SMALL CELL LUNG CANCER

Protocol #D5336C00001
A Phase II, Open label, Randomised, Multi-centre Study to Assess the Safety and Efficacy of Agents Targeting DNA Damage Repair in Combination with Olaparib versus Olaparib Monotherapy in the Treatment of Metastatic Triple Negative Breast Cancer Patients Stratified by Alterations in Homologous Recombinant Repair (HRR)-related Genes (including BRCA1/2)
(VIOLETTE)

Protocol #CA180653
Determining Change in Cardiovascular and Metabolic Risks in Patients with Chronic Phase Myeloid Leukemia Receiving BCR-ABL Tyrosine Kinase Inhibitor First-Line Therapy in the United States.
For more information please contact our research department at 606-487-7978.

Protocol #GTI-4419-301

ROMAN: Reduction in Oral Mucositis with Avasopasem Manganese (GC4419) – Phase 3 Trial in Patients Receiving Chemoradiotherapy for Locally-Advanced, Non-Metastatic Head and Neck Cancer.

To view the Open Clinical Trials offered by UK Markey please follow link below.
http://ukhealthcare.uky.edu/markey/Researchers/Clinical-Trials/Find-a-Clinical-Trial/